Description
Evodine, the major limonoid of Evodiae Fuctus, is a potent P-gp inhibitor. Evodine has protection against glutamateinduced toxicity by preserving the antioxidant defense system.
Product information
CAS Number: 6989-38-4
Molecular Weight: 329.35
Formula: C18H19NO5
Chemical Name: 1-({4,8-dimethoxyfuro[2,3-b]quinolin-7-yl}oxy)-3-methylbut-3-en-2-ol
Smiles: CC(=C)C(O)COC1=CC=C2C(N=C3OC=CC3=C2OC)=C1OC
InChiKey: LNJTUUHDKCPQAA-UHFFFAOYSA-N
InChi: InChI=1S/C18H19NO5/c1-10(2)13(20)9-24-14-6-5-11-15(17(14)22-4)19-18-12(7-8-23-18)16(11)21-3/h5-8,13,20H,1,9H2,2-4H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Xia YY, et al. Simultaneous determination of evodiamine and evodine in Beagle dog plasma using liquidchromatography tandem mass spectrometry. J Asian Nat Prod Res. 2013;15(3):235-43.
Products are for research use only. Not for human use.
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