Catalog No. Size PriceQuantity
M13420-2 Contact for quotation $100
M13420-10 Contact for quotation $100


VU0652835 is a metabotropic glutamate receptor subtype 5 (mGlu5) negative allosteric modulator with an IC50 of 81 nM.

Product information

CAS Number: 1848252-81-2

Molecular Weight: 333.41

Formula: C16H19N3O3S

Chemical Name: 6-methyl-N-(4-methyl-1,3-thiazol-2-yl)-4-{[(3R,5R)-5-methyloxolan-3-yl]oxy}pyridine-2-carboxamide

Smiles: C[C@@H]1C[C@H](CO1)OC1C=C(C)N=C(C=1)C(=O)NC1=NC(C)=CS1


InChi: InChI=1S/C16H19N3O3S/c1-9-4-12(22-13-5-11(3)21-7-13)6-14(17-9)15(20)19-16-18-10(2)8-23-16/h4,6,8,11,13H,5,7H2,1-3H3,(H,18,19,20)/t11-,13-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Felts AS, et al. Discovery of 4-alkoxy-6-methylpicolinamide negative allosteric modulators of metabotropic glutamate receptor subtype 5. Bioorg Med Chem Lett. 2019 Jan 1;29(1):47-50.

Products are for research use only. Not for human use.

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