5β-Dihydrocortisone


Catalog No. Size PriceQuantity
M13448-2 2mg solid $95
M13448-10 10mg solid $285

Description

5β-Dihydrocortisone is a sterol metabolite of cortisone by 5β-reductase (AKR1D1) in liver.

Product information

CAS Number: 68-54-2

Molecular Weight: 362.46

Formula: C21H30O5

Chemical Name: (1R,3aS,3bS,5aR,9aS,9bS,11aS)-3a,3b,5a,9b-tetrahydrogenio-1-hydroxy-1-(2-hydroxyacetyl)-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthrene-7,10-dione

Smiles: C[C@]12CC(=O)[C@H]3[C@@H](CC[C@@H]4CC(=O)CC[C@@]43C)[C@@H]1CC[C@]2(O)C(=O)CO

InChiKey: YCLWEYIBFOLMEM-FNLRALKVSA-N

InChi: InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12,14-15,18,22,26H,3-11H2,1-2H3/t12-,14+,15+,18-,19+,20+,21+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (275.89 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Nikolaos Nikolaou, et al. AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells. J Steroid Biochem Mol Biol

Products are for research use only. Not for human use.

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