β-Amyloid (1-9)


Catalog No. Size PriceQuantity
M13654-2 Contact sales@xcessbio.com for quotation $100

Description

β-Amyloid (1-9), an N-terminal fragment of beta amyloid, consists of amino acid residues 1 to 9. β-Amyloid (1-9) contains a B cell epitope, but it does not include T cell epitopes. Omission of residues 1 to 9 from the full-length Alzheimer'sβ-Amyloid peptide 1 to 40 does not prevent the peptide from forming amyloid fibrils or eliminate fibril polymorphism .

Product information

CAS Number: 147529-30-4

Molecular Weight: 1033.01

Formula: C42H60N14O17

Chemical Name: (5S, 8S, 11S, 14S, 17S, 20S, 26S)-11-((1H-imidazol-5-yl)methyl)-26-amino-17-benzyl-20-(2-carboxyethyl)-8-(carboxymethyl)-14-(3-(diaminomethyleneamino)propyl)-5-(hydroxymethyl)-23-methyl-4, 7, 10, 13, 16, 19, 22, 25-octaoxo-3, 6, 9, 12, 15, 18, 21, 24-octaazaoctacosane-1, 28-dioic acid

Smiles: CC(NC(=O)[C@@H](N)CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1C=CC=CC=1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)NCC(O)=O

InChiKey: BRRKPUCEVBBGNV-ZDLFWEFWSA-N

InChi: InChI=1S/C42H60N14O17/c1-20(50-35(67)23(43)14-31(60)61)34(66)51-25(9-10-30(58)59)38(70)53-26(12-21-6-3-2-4-7-21)39(71)52-24(8-5-11-47-42(44)45)37(69)54-27(13-22-16-46-19-49-22)40(72)55-28(15-32(62)63)41(73)56-29(18-57)36(68)48-17-33(64)65/h2-4,6-7,16,19-20,23-29,57H,5,8-15,17-18,43H2,1H3,(H,46,49)(H,48,68)(H,50,67)(H,51,66)(H,52,71)(H,53,70)(H,54,69)(H,55,72)(H,56,73)(H,58,59)(H,60,61)(H,62,63)(H,64,65)(H4,44,45,47)/t20?,23-,24-,25-,26-,27-,28-,29-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Zamora E, et al. Papillomavirus-like particles are an effective platform for amyloid-beta immunization in rabbitsand transgenic mice. J Immunol. 2006 Aug 15;177(4):2662-2670.
  2. Paravastu AK, et al. Polymorphic fibril formation by residues 10-40 of the Alzheimer's beta-amyloid peptide. Biophys J. 2006 Jun 15;90(12):4618-29.

Products are for research use only. Not for human use.

Payment & Security

American Express Diners Club Discover JCB Mastercard PayPal Venmo Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed