Phorbol


Catalog No. Size PriceQuantity
M13661-2 2mg solid $85
M13661-10 10mg solid $255

Description

Phorbol is a highly toxic diterpene, whose esters have important biological properties.

Product information

CAS Number: 17673-25-5

Molecular Weight: 364.43

Formula: C20H28O6

Synonym:

4β-Phorbol

Chemical Name: (1S,2S,6R,10S,11R,13S,14R,15R)-2,10,11-trihydrogenio-1,6,13,14-tetrahydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyltetracyclo[8.5.0.0²,⁶.0¹¹,¹³]pentadeca-3,8-dien-5-one

Smiles: CC1(C)[C@H]2[C@@H]3C=C(C[C@@]4(O)[C@@H](C=C(C)C4=O)[C@@]3(O)[C@H](C)[C@@H](O)[C@@]12O)CO

InChiKey: QGVLYPPODPLXMB-UBTYZVCOSA-N

InChi: InChI=1S/C20H28O6/c1-9-5-13-18(24,15(9)22)7-11(8-21)6-12-14-17(3,4)20(14,26)16(23)10(2)19(12,13)25/h5-6,10,12-14,16,21,23-26H,7-8H2,1-4H3/t10-,12+,13-,14-,16-,18-,19-,20-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 66.67 mg/mL (182.94 mM; Need ultrasonic). H2O : ≥ 20 mg/mL (54.88 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Matsuzawa Y, et al. Activation of cytosolic phospholipase A2alpha by epidermal growth factor (EGF) and phorbol ester in HeLa cells: different effects of inhibitors for EGF receptor, protein kinase C, Src, and C-Raf. J Pharmacol Sci. 2009 Oct;111(2):182-92

Products are for research use only. Not for human use.

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