CS-2660 (JNJ-38158471)

Catalog No. Size PriceQuantity
M13698-2 Contact sales@xcessbio.com for quotation $100


CS-2660 (JNJ-38158471) is a well tolerated, orally available, highly selective VEGFR-2 inhibitor with IC50 of 40 nM. CS-2660 (JNJ-38158471) also inhibits closely related tyrosine kinases such as RET (c-RET) and Kit (c-Kit) with IC50 of 180 nM and 500 nM,while it has no significant activity (>1 microM) against VEGFR-1 and VEGFR-3.

Product information

CAS Number: 951151-97-6

Molecular Weight: 364.79

Formula: C15H17ClN6O3

Chemical Name: 1-[4-({6-amino-5-[(methoxyimino)methyl]pyrimidin-4-yl}oxy)-2-chlorophenyl]-3-ethylurea

Smiles: CON=CC1=C(N)N=CN=C1OC1C=CC(NC(=O)NCC)=C(Cl)C=1


InChi: InChI=1S/C15H17ClN6O3/c1-3-18-15(23)22-12-5-4-9(6-11(12)16)25-14-10(7-21-24-2)13(17)19-8-20-14/h4-8H,3H2,1-2H3,(H2,17,19,20)(H2,18,22,23)/b21-7+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Solubility (25°C). 30 mg/mL(82.23 mM). Insoluble.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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