β-Amyloid (4-10)


Catalog No. Size PriceQuantity
M13718-2 Contact sales@xcessbio.com for quotation $100

Description

β-Amyloid (4-10) is an epitope for the polyclonal anti-Aβ(1-42) antibody, reduces amyloid deposition in a transgenic Alzheimer disease mouse model.

Product information

CAS Number: 477284-32-5

Molecular Weight: 880.90

Formula: C39H52N12O12

Chemical Name: (6S, 9S, 12S, 15S, 21S)-9-((1H-imidazol-4-yl)methyl)-1-amino-6-((S)-2-amino-3-phenylpropanamido)-12-(carboxymethyl)-21-(4-hydroxybenzyl)-15-(hydroxymethyl)-1-imino-7, 10, 13, 16, 19-pentaoxo-2, 8, 11, 14, 17, 20-hexaazadocosan-22-oic acid

Smiles: NC(=N)NCCC[C@H](NC(=O)[C@@H](N)CC1C=CC=CC=1)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC1C=CC(O)=CC=1)C(O)=O

InChiKey: IQIYXVLANRIFFC-WPMUBMLPSA-N

InChi: InChI=1S/C39H52N12O12/c40-25(13-21-5-2-1-3-6-21)33(57)48-26(7-4-12-44-39(41)42)35(59)49-27(15-23-17-43-20-46-23)36(60)50-28(16-32(55)56)37(61)51-30(19-52)34(58)45-18-31(54)47-29(38(62)63)14-22-8-10-24(53)11-9-22/h1-3,5-6,8-11,17,20,25-30,52-53H,4,7,12-16,18-19,40H2,(H,43,46)(H,45,58)(H,47,54)(H,48,57)(H,49,59)(H,50,60)(H,51,61)(H,55,56)(H,62,63)(H4,41,42,44)/t25-,26-,27-,28-,29-,30-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. tefanescu R1, et al. Molecular characterization of the β-amyloid(4-10) epitope of plaque specific Aβ antibodies by affinity-mass spectrometry using alanine site mutation. J Pept Sci. 2018 Jan;24(1).

Products are for research use only. Not for human use.

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