Bis-PEG2-acid


Catalog No. Size PriceQuantity
M13724-2 2mg solid $75
M13724-10 10mg solid $225

Description

Bis-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Product information

CAS Number: 19364-66-0

Molecular Weight: 206.19

Formula: C8H14O6

Chemical Name: 3-[2-(2-carboxyethoxy)ethoxy]propanoic acid

Smiles: OC(=O)CCOCCOCCC(O)=O

InChiKey: BOXWYBCUJGWEOJ-UHFFFAOYSA-N

InChi: InChI=1S/C8H14O6/c9-7(10)1-3-13-5-6-14-4-2-8(11)12/h1-6H2,(H,9,10)(H,11,12)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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