(rel)-Tranylcypromine D5 hydrochloride


Catalog No. Size PriceQuantity
M13826-2 2mg solid $1,275
M13826-10 10mg solid $5,100

Description

(rel)-Tranylcypromine D5 hydrochloride (2-Phenylcyclopropylamine D5 hydrochloride) is a deuterium labeled (rel)-Tranylcypromine hydrochloride. (rel)-Tranylcypromine hydrochloride is an irreversible, nonselective monoamine oxidase (MAO) inhibitor used in the treatment of depression. (rel)-Tranylcypromine hydrochloride is also a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis.

Product information

CAS Number: 107077-98-5

Molecular Weight: 174.68

Formula: C9H12ClN

Synonym:

2-Phenylcyclopropylamine D5 hydrochloride

Chemical Name: (1R,2S)-2-[(2,3,4,5,6-²H₅)phenyl]cyclopropan-1-amine hydrochloride

Smiles: Cl.[2H]C1=C([C@@H]2C[C@H]2N)C([2H])=C([2H])C([2H])=C1[2H] |&1:4,6|

InChiKey: ZPEFMSTTZXJOTM-KMWRGRSGSA-N

InChi: InChI=1S/C9H11N.ClH/c10-9-6-8(9)7-4-2-1-3-5-7;/h1-5,8-9H,6,10H2;1H/t8-,9+;/m0./s1/i1D,2D,3D,4D,5D;

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Caraci F, et al. Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity. Eur J Pharmacol. 2015 Oct 5;764:256-263.
  2. Sun Q, et al. Tranylcypromine, a lysine-specific demethylase 1 (LSD1) inhibitor, suppresses lesion growth and improves generalized hyperalgesia in mouse with induced endometriosis. Reprod Biol Endocrinol. 2016 Apr 9;14:17.

Products are for research use only. Not for human use.

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