Chloralose


Catalog No. Size PriceQuantity
M13844-2 Contact sales@xcessbio.com for quotation $100

Description

Chloralose (α-Chloralose) is a central nervous system depressant. Chloralose (α-Chloralose) allosterically modulates GABAA receptor activity and binds to a site on the GABAA receptor complex, neurosteroid, and barbiturate sites.

Product information

CAS Number: 15879-93-3

Molecular Weight: 309.53

Formula: C8H11Cl3O6

Chemical Name: (1R)-1-[(2R,3aR,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)-tetrahydro-2H-furo[2,3-d][1,3]dioxol-5-yl]ethane-1,2-diol

Smiles: OC[C@@H](O)[C@H]1O[C@@H]2O[C@@H](O[C@@H]2[C@H]1O)C(Cl)(Cl)Cl

InChiKey: OJYGBLRPYBAHRT-IPQSZEQASA-N

InChi: InChI=1S/C8H11Cl3O6/c9-8(10,11)7-16-5-3(14)4(2(13)1-12)15-6(5)17-7/h2-7,12-14H,1H2/t2-,3+,4-,5-,6-,7-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 100 mg/mL (323.07 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Chloralose (α-Chloralose) activates the gama-aminobutyric acid (GABA)-induced chloride conductance of gama-aminobutyric acidA (GABAA) receptors expressed in Xenopus laevis oocytes with an EC50 value of 49 μM

Products are for research use only. Not for human use.

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