Oxolamine citrate

Oxolamine citrate (SKF-9976 citrate) is a cough suppressant that can be used for the research of respiratory tract diseases. Oxolamine citrate also exhibits anti-inflammatory effect.

Product information

CAS Number: 1949-20-8

Molecular Weight: 437.44

Formula: C20H27N3O8

Synonym:

SKF-9976 citrate

AF-438 citrate

Chemical Name: 2-hydroxypropane-1,2,3-tricarboxylic acid; diethyl[2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethyl]amine

Smiles: CCN(CCC1=NC(=NO1)C1C=CC=CC=1)CC.OC(=O)C(O)(CC(O)=O)CC(O)=O

InChiKey: RBZIGQJSMCOHSS-UHFFFAOYSA-N

InChi: InChI=1S/C14H19N3O.C6H8O7/c1-3-17(4-2)11-10-13-15-14(16-18-13)12-8-6-5-7-9-12;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-9H,3-4,10-11H2,1-2H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 100 mg/mL (228.60 mM). H2O : 14.29 mg/mL (32.67 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Kirilmaz L, et, al. Sustained-release dosage form of oxolamine citrate: preparation and release kinetics. J Microencapsul. Apr-Jun 1992;9(2):167-72.
2. GIUDICI G, et, al. [On the anti-inflammatory action of oxolamine citrate]. Minerva Med. 1961 Oct 31;52:3752-5.

Products are for research use only. Not for human use.