Description
Propargyl-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Product information
CAS Number: 1818294-29-9
Molecular Weight: 448.55
Formula: C22H40O9
Chemical Name: tert-butyl 4,7,10,13,16,19,22-heptaoxapentacos-24-ynoate
Smiles: CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCC#C
InChiKey: ZYHHJKFUMHBJSI-UHFFFAOYSA-N
InChi: InChI=1S/C22H40O9/c1-5-7-24-9-11-26-13-15-28-17-19-30-20-18-29-16-14-27-12-10-25-8-6-21(23)31-22(2,3)4/h1H,6-20H2,2-4H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References:
- Noah Bell, et al. Compounds and methods for inhibiting phosphate transport. WO2012054110A2.
Products are for research use only. Not for human use.
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