C25-140


Catalog No. Size PriceQuantity
M14012-2 Contact sales@xcessbio.com for quotation $100

Description

C25-140 is a small-molecule inhibitor of TRAF6-Ubc13 interaction. C25-140 directly binds to TRAF6, thereby blocking the interaction of TRAF6 with Ubc13, and as a consequence lowers TRAF6 activity. C25-140 impedes NF-κB activation in various immune and inflammatory signaling pathways also in primary human and murine cells.

Product information

CAS Number: 1358099-18-9

Molecular Weight: 457.57

Formula: C26H31N7O

Chemical Name: 1-(4-benzylpiperidin-1-yl)-3-(3,5-dimethyl-1-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}-1H-pyrazol-4-yl)propan-1-one

Smiles: CC1=C(CCC(=O)N2CCC(CC3C=CC=CC=3)CC2)C(C)=NN1C1C=CC2=NN=C(C)N2N=1

InChiKey: HFKVRXVHZGBRKF-UHFFFAOYSA-N

InChi: InChI=1S/C26H31N7O/c1-18-23(19(2)32(29-18)25-11-10-24-28-27-20(3)33(24)30-25)9-12-26(34)31-15-13-22(14-16-31)17-21-7-5-4-6-8-21/h4-8,10-11,22H,9,12-17H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Solubility (25°C). 92 mg/mL(201.06 mM). Insoluble.

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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