Acetylisovaleryltylosin Tartrate


Catalog No. Size PriceQuantity
M14080-2 2mg solid $85
M14080-10 10mg solid $255

Description

Acetylisovaleryltylosin tartrate (AK105039) is an antimicrobial of the macrolide group with antibacterial activity against Gram-positive bacteria.

Product information

CAS Number: 63428-13-7

Molecular Weight: 1192.34

Formula: C57H93NO25

Synonym:

Acetylisovaleryltylo​sin tartrate

Chemical Name: 2,3-dihydroxybutanedioic acid; 6-({12-[(5-{[5-(acetyloxy)-4-hydroxy-4,6-dimethyloxan-2-yl]oxy}-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl)oxy]-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)-1-oxacyclohexadeca-4,6-dien-3-yl}methoxy)-4,5-dimethoxy-2-methyloxan-3-yl 3-methylbutanoate

Smiles: CC(C)CC(=O)OC1C(OC)C(OC)C(OC1C)OCC1C=C(C)C=CC(=O)C(C)CC(CC=O)C(OC2OC(C)C(OC3CC(C)(O)C(OC(C)=O)C(C)O3)C(C2O)N(C)C)C(C)C(O)CC(=O)OC1CC.OC(C(O)C(O)=O)C(O)=O

InChiKey: KWXNNLFPPKMIJU-XOPSLJOJSA-N

InChi: InChI=1S/C53H87NO19.C4H6O6/c1-16-39-36(26-65-52-49(64-15)48(63-14)47(32(8)68-52)71-40(59)21-27(2)3)22-28(4)17-18-37(57)29(5)23-35(19-20-55)45(30(6)38(58)24-41(60)70-39)73-51-44(61)43(54(12)13)46(31(7)67-51)72-42-25-53(11,62)50(33(9)66-42)69-34(10)56;5-1(3(7)8)2(6)4(9)10/h17-18,20,22,27,29-33,35-36,38-39,42-52,58,61-62H,16,19,21,23-26H2,1-15H3;1-2,5-6H,(H,7,8)(H,9,10)/b18-17-,28-22-;

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Solubility (25°C). 100 mg/mL(83.86 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Feng-yu Deng, et al. Characterization of the Interaction between Acetylisovaleryltylosin Tartrat and Bovine Serum Albumin without or with Zn2+ and Cu2+ by Spectroscopic Analysis. Guang Pu Xue Yu Guang Pu Fen Xi. 2016 Jul;36(7):2351-7.
  2. R Okamoto, et al. The activity of 4''-acylated tylosin derivatives against macrolide-resistant gram-positive bacteria. J Antibiot (Tokyo). 1979 May;32(5):542-4.

Products are for research use only. Not for human use.

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