Description
Epanolol (Visacor; ICI141292) is a potent β-adrenoceptor partial agonist with a greater affinity for β1- than β2-adrenoceptors.
Product information
CAS Number: 86880-51-5
Molecular Weight: 369.41
Formula: C20H23N3O4
Synonym:
Visacor
ICI141292
Chemical Name: N-(2-{[3-(2-cyanophenoxy)-2-hydroxypropyl]amino}ethyl)-2-(4-hydroxyphenyl)acetamide
Smiles: N#CC1=CC=CC=C1OCC(O)CNCCNC(=O)CC1=CC=C(O)C=C1
InChiKey: YARKMNAWFIMDKV-UHFFFAOYSA-N
InChi: InChI=1S/C20H23N3O4/c21-12-16-3-1-2-4-19(16)27-14-18(25)13-22-9-10-23-20(26)11-15-5-7-17(24)8-6-15/h1-8,18,22,24-25H,9-11,13-14H2,(H,23,26)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Epanolol is a novel anti-anginal agent which is a β1-adrenoceptor partial agonist exhibiting selective β1-adrenoceptor antagonist and selective β1-adrenoceptor agonist activity.
References:
- Hosie J, et al. Pharmacokinetics of epanolol after acute and chronic oral dosing in elderly patients with stable angina pectoris. Br J Clin Pharmacol. 1990 Mar;29(3):333-7.
Products are for research use only. Not for human use.
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