1, 4-Chrysenequinone


Catalog No. Size PriceQuantity
M14512-2 2mg solid $85
M14512-10 10mg solid $255

Description

1,4-Chrysenequinone, a polycyclic aromatic quinone, acts as an activator of aryl hydrocarbon receptor (AhR).

Product information

CAS Number: 100900-16-1

Molecular Weight: 258.27

Formula: C18H10O2

Synonym:

Chrysene-1,4-dione

Chemical Name: 1,4-dihydrochrysene-1,4-dione

Smiles: O=C1C=CC(=O)C2C=CC3C4=CC=CC=C4C=CC=3C1=2

InChiKey: UORKIKBNUWJNJF-UHFFFAOYSA-N

InChi: InChI=1S/C18H10O2/c19-16-9-10-17(20)18-14-6-5-11-3-1-2-4-12(11)13(14)7-8-15(16)18/h1-10H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 3.33 mg/mL (12.89 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

1,4-Chrysenequinone shows significant AhR ligand activity, with ECTCDD25s (concentration equivalent with 25% of TCDD max) of 9.7 nM and 1.9 μM in yeast and mouse hepatoma cell systems, respectively.

References:

  1. Misaki K, et al. Aryl hydrocarbon receptor ligand activity of polycyclic aromatic ketones and polycyclic aromatic quinones. Environ Toxicol Chem. 2007 Jul;26(7):1370-9.

Products are for research use only. Not for human use.

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