3', 4', 5', 5, 7-Pentamethoxyflavone


Catalog No. Size PriceQuantity
M14671-2 Contact sales@xcessbio.com for quotation $100

Description

3',4',5',5,7-Pentamethoxyflavone, a natural flavonoid extracted from Rutaceae plants, sensitizes chemoresistant cancer cells to chemotherapeutic drugs by inhibition of Nrf2 pathway.

Product information

CAS Number: 53350-26-8

Molecular Weight: 372.37

Formula: C20H20O7

Chemical Name: 5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-chromen-4-one

Smiles: COC1=CC(=CC(OC)=C1OC)C1=CC(=O)C2C(=CC(=CC=2OC)OC)O1

InChiKey: GIKVSFNAEBQLGB-UHFFFAOYSA-N

InChi: InChI=1S/C20H20O7/c1-22-12-8-15(23-2)19-13(21)10-14(27-16(19)9-12)11-6-17(24-3)20(26-5)18(7-11)25-4/h6-10H,1-5H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Hou X, et al. 3',4',5',5,7-pentamethoxyflavone sensitizes Cisplatin-resistant A549 cells to Cisplatin by inhibition of Nrf2 pathway. Mol Cells. 2015 May;38(5):396-401.

Products are for research use only. Not for human use.

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