Description
Saccharin is an orally active, non-caloric artificial sweeteners (NAS). Saccharin has bacteriostatic and microbiome-modulating properties.
Product information
CAS Number: 81-07-2
Molecular Weight: 183.18
Formula: C7H5NO3S
Chemical Name: 2,3-dihydro-1λ⁶,2-benzothiazole-1,1,3-trione
Smiles: O=C1NS(=O)(=O)C2C=CC=CC1=2
InChiKey: CVHZOJJKTDOEJC-UHFFFAOYSA-N
InChi: InChI=1S/C7H5NO3S/c9-7-5-3-1-2-4-6(5)12(10,11)8-7/h1-4H,(H,8,9)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
In vitro, saccharin (0.5, 2.5, 5 mM) inhibits bacterial growth in a species-dependent manner.
In Vivo:
In vivo, saccharin (oral; 5 mg/kg; twice a day) intake reduces fecal bacterial load and alters microbiome composition, while the intestinal barrier is not obviously affected in male C57BL/6JRj wild type (wt) mice.
Products are for research use only. Not for human use.
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