Description
Lenalidomide-C5-NH2 is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-NH2 can be connected to the ligand for protein by a linker to form PROTAC, such as MDM2 PROTAC degrader.
Product information
CAS Number: 2093388-45-3
Molecular Weight: 329.39
Formula: C18H23N3O3
Chemical Name: 3-[4-(5-aminopentyl)-1-oxo-2,3-dihydro-1H-isoindol-2-yl]piperidine-2,6-dione
Smiles: NCCCCCC1=CC=CC2=C1CN(C1CCC(=O)NC1=O)C2=O
InChiKey: ZZXXBKHLDNFHCQ-UHFFFAOYSA-N
InChi: InChI=1S/C18H23N3O3/c19-10-3-1-2-5-12-6-4-7-13-14(12)11-21(18(13)24)15-8-9-16(22)20-17(15)23/h4,6-7,15H,1-3,5,8-11,19H2,(H,20,22,23)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 5 mg/mL (15.18 mM; Need ultrasonic). H2O : 50 mg/mL (151.80 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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