Description
FATP1-IN-2, as an arylpiperazine derivative, is an orally active fatty acid transport protein 1 (FATP1) inhibitor (human IC50=0.43 μM, mouse IC50=0.39 μM).
Product information
CAS Number: 2650944-83-3
Molecular Weight: 353.39
Formula: C19H20FN5O
Chemical Name: 2-[4-(5-fluoropyridin-2-yl)piperazin-1-yl]-1-{2-methylimidazo[1,2-a]pyridin-3-yl}ethan-1-one
Smiles: CC1N=C2C=CC=CN2C=1C(=O)CN1CCN(CC1)C1=CC=C(F)C=N1
InChiKey: ZGLMIQGBDRQCKA-UHFFFAOYSA-N
InChi: InChI=1S/C19H20FN5O/c1-14-19(25-7-3-2-4-18(25)22-14)16(26)13-23-8-10-24(11-9-23)17-6-5-15(20)12-21-17/h2-7,12H,8-11,13H2,1H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
FATP1-IN-2 (10 mg/kg; p.o.) shows a Cmax value above the mouse IC50 value. FATP1-IN-2 (3, 10, 30 mg/kg; p.o.; 4 weeks) shows TG content of each tissue does not change at any dose.
Products are for research use only. Not for human use.
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