Description
Hexa His is an amino acid sequence consisting of 6 His residues in a row, it is also known as hexa histidine-tag, 6xHis-tag, and by the trademarked name His-tag. Hexa His Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. The form B is active against certain oligosaccharides. The form S has no measurable activity. Hexa His acts as a metal binding site for a recombinant protein. His-Tag sequence can be placed on the N- or -terminal of a target protein by using vectors from various commercial molecular biology companies. And this Tag is often followed by a cleavage site for a specific protease - for example Leu-Val-Arg-Gly-Ser peptide sequence is recognized and cleaved by the protease known as thrombin.
Product information
Molecular Weight: 840.85
Formula: C36H44N18O7
Chemical Name: 2-{2-[2-(2-{2-[2-amino-3-(1H-pyrazol-5-yl)propanamido]-3-(1H-pyrazol-5-yl)propanamido}-3-(1H-pyrazol-5-yl)propanamido)-3-(1H-pyrazol-5-yl)propanamido]-3-(1H-pyrazol-5-yl)propanamido}-3-(1H-pyrazol-5-yl)propanoic acid
Smiles: NC(CC1=CC=NN1)C(=O)NC(CC1=CC=NN1)C(=O)NC(CC1=CC=NN1)C(=O)NC(CC1=CC=NN1)C(=O)NC(CC1=CC=NN1)C(=O)NC(CC1=CC=NN1)C(O)=O
InChiKey: YGMLKSJTDNKYPA-UHFFFAOYSA-N
InChi: InChI=1S/C36H44N18O7/c37-25(13-19-1-7-38-49-19)31(55)44-26(14-20-2-8-39-50-20)32(56)45-27(15-21-3-9-40-51-21)33(57)46-28(16-22-4-10-41-52-22)34(58)47-29(17-23-5-11-42-53-23)35(59)48-30(36(60)61)18-24-6-12-43-54-24/h1-12,25-30H,13-18,37H2,(H,38,49)(H,39,50)(H,40,51)(H,41,52)(H,42,53)(H,43,54)(H,44,55)(H,45,56)(H,46,57)(H,47,58)(H,48,59)(H,60,61)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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