Description
Andrograpanin, a bioactive compound from Andrographis paniculata, exhibits anti-inflammatory and anti-infectious properties.
Product information
CAS Number: 82209-74-3
Molecular Weight: 318.45
Formula: C20H30O3
Chemical Name: 3-{2-[(1R, 4aS, 5R, 8aS)-5-(hydroxymethyl)-5, 8a-dimethyl-2-methylidene-decahydronaphthalen-1-yl]ethyl}-2, 5-dihydrofuran-2-one
Smiles: C[C@@]12CCC[C@@](C)(CO)[C@H]1CCC(=C)[C@H]2CCC1=CCOC1=O
InChiKey: WKKBRRFSRMDTJB-JYBIWHBTSA-N
InChi: InChI=1S/C20H30O3/c1-14-5-8-17-19(2,13-21)10-4-11-20(17,3)16(14)7-6-15-9-12-23-18(15)22/h9,16-17,21H,1,4-8,10-13H2,2-3H3/t16-,17-,19+,20+/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Andrograpanin exhibits anti-inflammatory properties in lipopolysaccharide-induced macrophage cells through down-regulating the p38 MAPKs signaling pathways. Andrograpanin enhances chemokine SDF-1α-induced leukocytes chemotaxis in Jurkat, THP-1 and PBL cells.
Products are for research use only. Not for human use.
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