Description
Chlorprothixene hydrochloride is a dopamine and histamine receptors antagonist with Kis of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively. Antipsychotic activity.
Product information
CAS Number: 6469-93-8
Molecular Weight: 352.32
Formula: C18H19Cl2NS
Chemical Name: (Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N, N-dimethylpropan-1-amine hydrochloride
Smiles: Cl.CN(C)CC/C=C1/C2=CC=CC=C2SC2=CC=C(Cl)C=C2/1
InChiKey: YWKRLOSRDGPEJR-KIUKIJHYSA-N
InChi: InChI=1S/C18H18ClNS.ClH/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18;/h3-4,6-10,12H,5,11H2,1-2H3;1H/b14-7-;
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 2.5 mg/mL (7.10 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Chlorprothixene binds to 5-HT receptors with pKis of 8.3, 8.5, and 9.4 for 5-HT7, 5-HT6 and 5-HT2, respectively.
Products are for research use only. Not for human use.
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