Chlorprothixene hydrochloride


Catalog No. Size PriceQuantity
M16291-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Chlorprothixene hydrochloride is a dopamine and histamine receptors antagonist with Kis of 18 nM, 2.96 nM, 4.56 nM, 9 nM and 3.75 nM for hD1, hD2, hD3, hD5 and hH1 receptors, respectively. Antipsychotic activity.

Product information

CAS Number: 6469-93-8

Molecular Weight: 352.32

Formula: C18H19Cl2NS

Chemical Name: (Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N, N-dimethylpropan-1-amine hydrochloride

Smiles: Cl.CN(C)CC/C=C1/C2=CC=CC=C2SC2=CC=C(Cl)C=C2/1

InChiKey: YWKRLOSRDGPEJR-KIUKIJHYSA-N

InChi: InChI=1S/C18H18ClNS.ClH/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18;/h3-4,6-10,12H,5,11H2,1-2H3;1H/b14-7-;

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 2.5 mg/mL (7.10 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Chlorprothixene binds to 5-HT receptors with pKis of 8.3, 8.5, and 9.4 for 5-HT7, 5-HT6 and 5-HT2, respectively.

Products are for research use only. Not for human use.

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