Description
Autogramin-1 potently inhibits autophagy induced by either starvation (IC50=0.17 μM) or mTORC1 inhibition (Rapamycin; IC50=0.44 μM).
Product information
CAS Number: 2375541-73-2
Molecular Weight: 485.56
Formula: C23H27N5O5S
Chemical Name: tert-butyl 2-(2,4-dioxo-3-propyl-1,2,3,4-tetrahydroquinazoline-7-amido)-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine-5-carboxylate
Smiles: CCCN1C(=O)C2C=CC(=CC=2NC1=O)C(=O)NC1=NC2CCN(CC=2S1)C(=O)OC(C)(C)C
InChiKey: SKCCDKMWKFQCQC-UHFFFAOYSA-N
InChi: InChI=1S/C23H27N5O5S/c1-5-9-28-19(30)14-7-6-13(11-16(14)25-21(28)31)18(29)26-20-24-15-8-10-27(12-17(15)34-20)22(32)33-23(2,3)4/h6-7,11H,5,8-10,12H2,1-4H3,(H,25,31)(H,24,26,29)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 6.94 mg/mL (14.29 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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