Description
C11-BODIPY581/591 is a fluorescent ratio-probe of lipid oxidation. C11-BODIPY581/591 is often used for indexing lipid peroxidation and antioxidant efficacy in model membrane systems and living cells. C11-BODIPY581/591 is applied in the quantitation of ferroptosis.
Product information
CAS Number: 217075-36-0
Molecular Weight: 504.42
Formula: C30H35BF2N2O2
Chemical Name: hydrogen 4-(10-carboxylatodecyl)-2,2-difluoro-12-[(1E,3E)-4-phenylbuta-1,3-dien-1-yl]-1λ⁵,3-diaza-2-boratricyclo[7.3.0.0³,⁷]dodeca-1(12),4,6,8,10-pentaen-1-ylium-2-uide
Smiles: [H+].[O-]C(=O)CCCCCCCCCCC1=CC=C2C=C3C=CC(/C=C/C=C/C4C=CC=CC=4)=[N+]3[B-](F)(F)N12
InChiKey: KXOYQMUYGHQCBT-CMQZKQKJSA-N
InChi: InChI=1S/C30H35BF2N2O2/c32-31(33)34-26(17-10-5-3-1-2-4-6-11-19-30(36)37)20-22-28(34)24-29-23-21-27(35(29)31)18-13-12-16-25-14-8-7-9-15-25/h7-9,12-16,18,20-24H,1-6,10-11,17,19H2,(H,36,37)/b16-12+,18-13+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
C11-BODIPY581/591 can easily enter membranes and exhibits good spectral separation of the nonoxidized (595 nm) and oxidized (520 nm) forms. Stock solutions of C11 BODIPY581/591 are made by dissolving 1 mg in 20 mM organic solvent. Cells are labeled in DMEM or PBS with 1-20 μM C11-BODIPY581/591 at 37°C, 30 min before the experiment. Alternatively, cells are incubated in DMEM with 1-10 μM preoxidized C11-BODIPY581/591.
Products are for research use only. Not for human use.
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