Description
Sisunatovir (RV521), an orally available inhibitor of the RSV fusion (RSV-F) protein, exhibits potent efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses, with IC50s of 1.4 nM and 1.0 nM, respectively.
Product information
CAS Number: 1903763-82-5
Molecular Weight: 446.44
Formula: C23H22F4N4O
Chemical Name: 1'-((5-(aminomethyl)-1-(4, 4, 4-trifluorobutyl)-1H-benzo[d]imidazol-2-yl)methyl)-6'-fluorospiro[cyclopropane-1, 3'-indolin]-2'-one
Smiles: NCC1=CC2N=C(CN3C(=O)C4(CC4)C4C=CC(F)=CC3=4)N(CCCC(F)(F)F)C=2C=C1
InChiKey: JOPCJJSYRPUEDS-UHFFFAOYSA-N
InChi: InChI=1S/C23H22F4N4O/c24-15-3-4-16-19(11-15)31(21(32)22(16)7-8-22)13-20-29-17-10-14(12-28)2-5-18(17)30(20)9-1-6-23(25,26)27/h2-5,10-11H,1,6-9,12-13,28H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 25 mg/mL (56.00 mM; ultrasonic and adjust pH to 3 with HCl).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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