CAY 10465


Catalog No. Size PriceQuantity
M16882-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

CAY 10465 is a selective and high-affinity AhR agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM).

Product information

CAS Number: 688348-33-6

Molecular Weight: 317.13

Formula: C15H9Cl2F3

Chemical Name: (E)-1, 3-dichloro-5-(4-(trifluoromethyl)styryl)benzene

Smiles: FC(F)(F)C1C=CC(/C=C/C2C=C(Cl)C=C(Cl)C=2)=CC=1

InChiKey: ISPYNXGXZRLLHM-OWOJBTEDSA-N

InChi: InChI=1S/C15H9Cl2F3/c16-13-7-11(8-14(17)9-13)2-1-10-3-5-12(6-4-10)15(18,19)20/h1-9H/b2-1+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 100 mg/mL (315.33 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

CAY 10465 (Compound 4i) is a selective and high-affinity AhR receptor agonist, with a Ki of 0.2 nM, and shows no effect on estrogen receptor (Ki >100000 nM). CAY 10465 (0.01 nM-100 μM) reduces apolipoprotein A-I (apo A-I) levels in HepG2 cells, and inhibits the synthesis of the protein.

Products are for research use only. Not for human use.

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