Description
A68930 hydrochloride, as a dopamine D1 receptor agonist, can be used for the research of bronchiectasis.
Product information
CAS Number: 130465-39-3
Molecular Weight: 307.77
Formula: C16H18ClNO3
Chemical Name: (1R,3S)-1-(aminomethyl)-3-phenyl-3,4-dihydro-1H-2-benzopyran-5,6-diol hydrochloride
Smiles: Cl.NC[C@@H]1O[C@@H](CC2=C1C=CC(O)=C2O)C1C=CC=CC=1
InChiKey: PQPGUUQPTSMLKU-YYLIZZNMSA-N
InChi: InChI=1S/C16H17NO3.ClH/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10;/h1-7,14-15,18-19H,8-9,17H2;1H/t14-,15-;/m0./s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
A68930 hydrochloride (1 μM; 5-60 minutes; 16HBE14o- or NCI-H292 cells) significantly increases phosphorylation of cAMP response element binding (CREB) protein. A68930 hydrochloride (1 μM; 48 hours; NCI-H292 cells) induces MUC5AC mRNA expression and increases the mRNA data of MUC5AC and MUC5AC protein expression. A68930 hydrochloride (1 μM; 20 minutes; NCI-H292 cells) significantly increases intracellular cAMP levels.
Products are for research use only. Not for human use.
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