JKE-1716


Catalog No. Size PriceQuantity
M17322-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

JKE-1716 is a potent and selective nitrolic acid-containing GPX4 inhibitor. JKE-1716 is able of inducing ferroptosis selectively through covalent GPX4 inhibition.

Product information

CAS Number: 2421118-05-8

Molecular Weight: 451.30

Formula: C20H20Cl2N4O4

Chemical Name: (Z)-3-{4-[bis(4-chlorophenyl)methyl]piperazin-1-yl}-N'-hydroxy-N,N,3-trioxopropanimidamide

Smiles: [O-][N+](=O)/C(/CC(=O)N1CCN(CC1)C(C1C=CC(Cl)=CC=1)C1C=CC(Cl)=CC=1)=N\O

InChiKey: HZFRTZXJNACSIE-NKFKGCMQSA-N

InChi: InChI=1S/C20H20Cl2N4O4/c21-16-5-1-14(2-6-16)20(15-3-7-17(22)8-4-15)25-11-9-24(10-12-25)19(27)13-18(23-28)26(29)30/h1-8,20,28H,9-13H2/b23-18-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

JKE-1716 (0~100 nΜ; 72 hours; LOX-IMVI cells) inhibits cell viability. JKE-1716 (LOX-IMVI cells) inhibits the expression of α-GPX4.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

You may also like

Recently viewed