Pericyazine - CAS# 2622-26-6


Catalog No. Size PriceQuantity
M17451-C Contact sales@xcessbio.com for quotation $100

Description

Pericyazine (Propericiazine) is a first-generation antipsychotic agent that is used as an adjunct to the short-term management of severe anxiety states and psychosis. Pericyazine is a selective D2-dopamine receptor antagonist. Pericyazine has adrenolytic, anticholinergic, and extrapyramidal effects.

Product information

CAS Number: 2622-26-6

Molecular Weight: 365.49

Formula: C21H23N3OS

Chemical Name: 10-[3-(4-hydroxypiperidin-1-yl)propyl]-10H-phenothiazine-2-carbonitrile

Smiles: N#CC1=CC2=C(C=C1)SC1C=CC=CC=1N2CCCN1CCC(O)CC1

InChiKey: LUALIOATIOESLM-UHFFFAOYSA-N

InChi: InChI=1S/C21H23N3OS/c22-15-16-6-7-21-19(14-16)24(18-4-1-2-5-20(18)26-21)11-3-10-23-12-8-17(25)9-13-23/h1-2,4-7,14,17,25H,3,8-13H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 250 mg/mL (684.01 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

Studies in rodents show that Pericyazine is able to produce potentiation of ether and hexobarbital narcosis and morphine analgesia. It also has hypothermic activity and produces depression of spontaneous motor activity in mice. On a milligram potency basis, Pericyazine is more potent than chlorpromizine in the potentiation of barbiturate narcosis test and the blocking of conditioned avoidance in rats. Pericyazine demonstrates analgesic properties similar to methotrimeprazine in mice and rats and produces adrenergic blocking effects in mice and dogs.

Products are for research use only. Not for human use.

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