BACE-1 inhibitor 2


Catalog No. Size PriceQuantity
M17507-C Contact sales@xcessbio.com for quotation $100

Description

BACE-1 inhibitor 2 is a potent and CNS permeable BACE-1 inhibitor with an IC50 of 1.5 nM in BACE-1 enzymatic assay.

Product information

Molecular Weight: 467.42

Formula: C21H21F4N5O3

Chemical Name: N-[3-[(4aS, 6S, 8aS)-2-amino-3, 3-difluoro-6-methyl-4a, 5, 6, 8-tetrahydro-4H-pyrano[3, 4-b]pyridin-8a-yl]-4-fluorophenyl]-5-(fluoromethoxy)pyrazine-2-carboxamide

Smiles: C[C@H]1C[C@H]2CC(F)(F)C(N)=N[C@]2(CO1)C1=CC(=CC=C1F)NC(=O)C1=CN=C(C=N1)OCF

InChiKey: QQHWYFAIJDVZQX-PVUDRZGPSA-N

InChi: InChI=1S/C21H21F4N5O3/c1-11-4-12-6-21(24,25)19(26)30-20(12,9-32-11)14-5-13(2-3-15(14)23)29-18(31)16-7-28-17(8-27-16)33-10-22/h2-3,5,7-8,11-12H,4,6,9-10H2,1H3,(H2,26,30)(H,29,31)/t11-,12-,20-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

BACE-1 inhibitor 2 inhibits Aβ42 production in human neuroblastoma cell lines with an IC50 of 3.5 nM.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed