Description
Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O2*- to hydrogen peroxide (H2O2), arresting the initiation of this cascade. Avasopasem manganese can be used for the research of severe oral mucositis (SOM) and cancer.
Product information
CAS Number: 435327-40-5
Molecular Weight: 483.38
Formula: C21H35Cl2MnN5
Chemical Name: manganese(2+) (4S, 9S, 14S, 19S)-3, 10, 13, 20, 26-pentaazatetracyclo[20.3.1.0, .0, ]hexacosa-1(26), 22, 24-triene dichloride
Smiles: [Cl-].[Cl-].[Mn+2].C1N[C@H]2CCCC[C@@H]2NCCN[C@H]2CCCC[C@@H]2NCC2=CC=CC1=N2
InChiKey: WXEMWBBXVXHEPU-NDOCQCNASA-L
InChi: InChI=1S/C21H35N5.2ClH.Mn/c1-3-10-20-18(8-1)22-12-13-23-19-9-2-4-11-21(19)25-15-17-7-5-6-16(26-17)14-24-20;;;/h5-7,18-25H,1-4,8-15H2;2*1H;/q;;;+2/p-2/t18-,19-,20-,21-;;;/m0.../s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
Avasopasem manganese is an agent intended to interrupt severe oral mucositis pathogenesis, to reduce the duration, incidence, and severity of radiation-induced oral mucositis.
Products are for research use only. Not for human use.
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