L-826266


Catalog No. Size PriceQuantity
M17542-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

L-826266 is a selective and competitive EP3 receptor antagonist. L-826266 can be used for convulsive disorders research.

Product information

CAS Number: 244101-03-9

Molecular Weight: 570.88

Formula: C27H21BrClNO4S

Chemical Name: (2E)-N-(5-bromo-2-methoxybenzenesulfonyl)-3-{5-chloro-2-[(naphthalen-2-yl)methyl]phenyl}prop-2-enamide

Smiles: COC1=CC=C(Br)C=C1S(=O)(=O)NC(=O)/C=C/C1=CC(Cl)=CC=C1CC1=CC2=CC=CC=C2C=C1

InChiKey: DYXFUJYHEDGCLS-UKTHLTGXSA-N

InChi: InChI=1S/C27H21BrClNO4S/c1-34-25-12-10-23(28)17-26(25)35(32,33)30-27(31)13-9-22-16-24(29)11-8-21(22)15-18-6-7-19-4-2-3-5-20(19)14-18/h2-14,16-17H,15H2,1H3,(H,30,31)/b13-9+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

In adult rat hippocampal slices, L-826266 (1 μM) prevents the PGE2-induced decrease of Na+,K+-ATPase activity.

In Vivo:

L-826266 (0.01-1 nmol/site; i.c.v.; once) delays seizures, and increases the latency for clonic and generalized tonic-clonic seizures induced by PTZ.

Products are for research use only. Not for human use.

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