PROTAC IRAK4 degrader-4


Catalog No. Size PriceQuantity
M17799-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

PROTAC IRAK4 degrader-4 is a PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1, compound I-127.

Product information

CAS Number: 2360528-45-4

Molecular Weight: 901.80

Formula: C41H38F3N11O10

Chemical Name: N-{3-carbamoyl-1-[4-({2-[2-(2-{[2-(2, 6-dioxopiperidin-3-yl)-1, 3-dioxoisoindol-4-yl]amino}ethoxy)ethoxy]ethyl}carbamoyl)phenyl]pyrazol-4-yl}-2-{2-[(2, 2, 2-trifluoroethyl)amino]pyridin-4-yl}-1, 3-oxazole-4-carboxamide

Smiles: NC(=O)C1=NN(C=C1NC(=O)C1=COC(=N1)C1=CC(NCC(F)(F)F)=NC=C1)C1C=CC(=CC=1)C(=O)NCCOCCOCCNC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

InChiKey: LFOAFZGTRKLOHG-UHFFFAOYSA-N

InChi: InChI=1S/C41H38F3N11O10/c42-41(43,44)21-49-30-18-23(10-11-47-30)38-51-28(20-65-38)36(59)50-27-19-54(53-33(27)34(45)57)24-6-4-22(5-7-24)35(58)48-13-15-64-17-16-63-14-12-46-26-3-1-2-25-32(26)40(62)55(39(25)61)29-8-9-31(56)52-37(29)60/h1-7,10-11,18-20,29,46H,8-9,12-17,21H2,(H2,45,57)(H,47,49)(H,48,58)(H,50,59)(H,52,56,60)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTAC IRAK4 degrader-4 is a PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader.

Products are for research use only. Not for human use.

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