Description
Eupalinolide O is a sesquiterpene lactone with anticancer activities. Eupalinolide O induces cell apoptosis in human MDA-MB-468 breast cancer cells.
Product information
CAS Number: 2170228-67-6
Molecular Weight: 418.44
Formula: C22H26O8
Chemical Name: (3aR, 4R, 9R, 11aR)-9-(acetyloxy)-6-formyl-10-methyl-3-methylidene-2-oxo-2H, 3H, 3aH, 4H, 5H, 8H, 9H, 11aH-cyclodeca[b]furan-4-yl (2E)-4-hydroxy-2-methylbut-2-enoate
Smiles: CC(=O)O[C@@H]1CC=C(C[C@@H](OC(=O)/C(/C)=C/CO)[C@@H]2[C@@H](C=C1C)OC(=O)C2=C)C=O |c:6,20|
InChiKey: MAIWERGSXNNKMK-HXFHGLJUSA-N
InChi: InChI=1S/C22H26O8/c1-12(7-8-23)21(26)29-19-10-16(11-24)5-6-17(28-15(4)25)13(2)9-18-20(19)14(3)22(27)30-18/h5,7,9,11,17-20,23H,3,6,8,10H2,1-2,4H3/b12-7+,13-9-,16-5+/t17-,18-,19-,20+/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Eupalinolide O could induce cell cycle arrest and apoptosis in human MDA-MB-468 breast cancer cells. Eupalinolide O also shows anti-TNBC (triple-negative breast cancer) activity against human MDA-MB-468 breast cancer cells.
Products are for research use only. Not for human use.
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