Oxytocin antiparallel dimer

Oxytocin antiparallel dimer is the disulfide-bridged homo peptide dimer.

Product information

CAS Number: 20054-93-7

Molecular Weight: 2014.37

Formula: C86H132N24O24S4

Chemical Name: (2S)-N-(carbamoylmethyl)-2-{[(2S)-1-[(4R, 7S, 10S, 13S, 16S, 19R, 24R, 27S, 30S, 33S, 36S, 39R)-19, 39-diamino-13, 33-bis[(2S)-butan-2-yl]-10, 30-bis(2-carbamoylethyl)-7, 27-bis(carbamoylmethyl)-24-[(2S)-2-{[(1S)-1-[(carbamoylmethyl)carbamoyl]-3-methylbutyl]carbamoyl}pyrrolidine-1-carbonyl]-16, 36-bis[(4-hydroxyphenyl)methyl]-6, 9, 12, 15, 18, 26, 29, 32, 35, 38-decaoxo-1, 2, 21, 22-tetrathia-5, 8, 11, 14, 17, 25, 28, 31, 34, 37-decaazacyclotetracontane-4-carbonyl]pyrrolidin-2-yl]formamido}-4-methylpentanamide

Smiles: CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CC2C=CC(O)=CC=2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@H](N)C(=O)N[C@@H](CC2C=CC(O)=CC=2)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)C(=O)NCC(N)=O

InChiKey: SBLVMJOXVMBHCL-AQFNFDSMSA-N

InChi: InChI=1S/C86H132N24O24S4/c1-9-43(7)69-83(131)97-51(23-25-63(89)113)75(123)101-57(33-65(91)115)77(125)105-59(85(133)109-27-11-13-61(109)81(129)103-53(29-41(3)4)73(121)95-35-67(93)117)39-138-136-38-50(88)72(120)100-56(32-46-17-21-48(112)22-18-46)80(128)108-70(44(8)10-2)84(132)98-52(24-26-64(90)114)76(124)102-58(34-66(92)116)78(126)106-60(40-137-135-37-49(87)71(119)99-55(79(127)107-69)31-45-15-19-47(111)20-16-45)86(134)110-28-12-14-62(110)82(130)104-54(30-42(5)6)74(122)96-36-68(94)118/h15-22,41-44,49-62,69-70,111-112H,9-14,23-40,87-88H2,1-8H3,(H2,89,113)(H2,90,114)(H2,91,115)(H2,92,116)(H2,93,117)(H2,94,118)(H,95,121)(H,96,122)(H,97,131)(H,98,132)(H,99,119)(H,100,120)(H,101,123)(H,102,124)(H,103,129)(H,104,130)(H,105,125)(H,106,126)(H,107,127)(H,108,128)/t43-,44-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,69-,70-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

The parallel and antiparallel homo and hetero bis-cystine dimers of oxytocin and deamino-oxytocin show biological activities ranged from 0.2% to 6% that of oxytocin.

References:

1. Chen L, et al. Syntheses and biological activities of parallel and antiparallel homo and hetero bis-cystine dimers of oxytocin and deamino-oxytocin. Pept Res. 1996;9(3):114-121.

Products are for research use only. Not for human use.