Description
Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor extracted from patent WO2009123623A1, has a Ki of <20 nM.
Product information
CAS Number: 1017931-53-1
Molecular Weight: 421.38
Formula: C19H21F6N3O
Chemical Name: (2S)-N-(1-cyanocyclopropyl)-4,4-difluoro-2-{[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]amino}heptanamide
Smiles: CCCC(F)(F)C[C@H](N[C@@H](C1C=CC(F)=CC=1)C(F)(F)F)C(=O)NC1(CC1)C#N
InChiKey: SPJXTKFUGDUWFY-GJZGRUSLSA-N
InChi: InChI=1S/C19H21F6N3O/c1-2-7-18(21,22)10-14(16(29)28-17(11-26)8-9-17)27-15(19(23,24)25)12-3-5-13(20)6-4-12/h3-6,14-15,27H,2,7-10H2,1H3,(H,28,29)/t14-,15-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Cathepsin Inhibitor 2 (Please refer to paragraph 0229 for detailed information) potently inhibits Cathepsin S, Cathepsin F, Cathepsin L, and Cathepsin B with Kis of <20 nM, 21-500 nM, 21-500 nM, and 21-500 nM, respectively.
Products are for research use only. Not for human use.
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