Description
CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3 ng/mL.
Product information
CAS Number: 205187-53-7
Molecular Weight: 348.27
Formula: C14H8F4O4S
Chemical Name: 3-fluoro-7-(2,2,2-trifluoroethoxy)-10λ⁶-phenoxathiine-10,10-dione
Smiles: O=S1(=O)C2=CC=C(F)C=C2OC2C=C(C=CC1=2)OCC(F)(F)F
InChiKey: PDIMOTRDGUQMNY-UHFFFAOYSA-N
InChi: InChI=1S/C14H8F4O4S/c15-8-1-3-12-10(5-8)22-11-6-9(21-7-14(16,17)18)2-4-13(11)23(12,19)20/h1-6H,7H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3 ng/mL. CX-157 is an investigational compound currently in development for the treatment of major depressive disorder (MDD). Mechanistic studies in animals have shown that CX-157 acts to inhibit MAO-A activity in a reversible and competitive manner, elevating brain levels of monoamine neurotransmitters.
Products are for research use only. Not for human use.
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