Description
Kuwanon A is a flavone derivative isolated from the root barks of the mulberry tree (Morus alba L.); inhibits nitric oxide production with an IC50 of 10.5 μM.
Product information
CAS Number: 62949-77-3
Molecular Weight: 420.45
Formula: C25H24O6
Chemical Name: 5,5',7-trihydroxy-2',2'-dimethyl-3-(3-methylbut-2-en-1-yl)-2'H,4H-[2,8'-bichromen]-4-one
Smiles: CC(C)=CCC1=C(OC2=CC(O)=CC(O)=C2C1=O)C1C=CC(O)=C2C=CC(C)(C)OC=12
InChiKey: DBUNRZUFILGKHP-UHFFFAOYSA-N
InChi: InChI=1S/C25H24O6/c1-13(2)5-6-16-22(29)21-19(28)11-14(26)12-20(21)30-23(16)17-7-8-18(27)15-9-10-25(3,4)31-24(15)17/h5,7-12,26-28H,6H2,1-4H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Kuwanon A shows significant inhibitory activity towards the differentiation of 3T3-L1 adipocytes with TG inhibition values of 47.1%. Kuwanon A also shows significant nitric oxide (NO) production inhibitory effects in RAW264.7 cells with an IC50 of 10.5 μM.
Products are for research use only. Not for human use.
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