Description
Colistin methanesulfonate sodium salt exhibits MIC values ranged from 4 to 16 mg/liter against susceptible strains (P. aeruginosa).
Product information
CAS Number: 8068-28-8
Molecular Weight: 1703.84
Formula: C58H105N16Na3O28S5
Chemical Name: trisodium (Z)-N-{1-[(Z)-{2-hydroxy-1-[(Z)-{3-[(sulfomethyl)amino]-1-[(Z)-[2,5,11,14-tetrahydroxy-3-(1-hydroxyethyl)-12,15-bis(2-methylpropyl)-8,17,20-trioxido-6,9,18-tris({2-[(sulfomethyl)amino]ethyl})-1,4,7,10,13,16,19-heptaazacyclotricosa-1,4,7,10,13,16,19-heptaen-21-yl]carboximidato]propyl}-C-hydroxycarbonimidoyl]propyl}-C-hydroxycarbonimidoyl]-3-[(sulfomethyl)amino]propyl}-6-methyloctanimidate
Smiles: [Na+].[Na+].[Na+].CCC(C)CCCC/C(/[O-])=N/C(CCNCS(O)(=O)=O)/C(/O)=N/C(C(C)O)/C(/O)=N/C(CCNCS(O)(=O)=O)/C(/[O-])=N/C1CCN=C(O)C(N=C(O)C(CCNCS(O)(=O)=O)N=C([O-])C(CCNCS(O)(=O)=O)N=C(O)C(CC(C)C)N=C(O)C(CC(C)C)N=C([O-])C(CCNCS(O)(=O)=O)N=C1[O-])C(C)O |c:45,61,73,81,89,t:49,101|
InChiKey: YEWZENBBZJKHEJ-UHFFFAOYSA-I
InChi: InChI=1S/C58H110N16O28S5.3Na/c1-9-35(6)12-10-11-13-46(77)65-38(14-20-59-28-103(88,89)90)53(82)74-48(37(8)76)58(87)70-41(17-23-62-31-106(97,98)99)50(79)68-43-19-25-64-57(86)47(36(7)75)73-54(83)42(18-24-63-32-107(100,101)102)67-49(78)39(15-21-60-29-104(91,92)93)69-55(84)44(26-33(2)3)72-56(85)45(27-34(4)5)71-52(81)40(66-51(43)80)16-22-61-30-105(94,95)96;;;/h33-45,47-48,59-63,75-76H,9-32H2,1-8H3,(H,64,86)(H,65,77)(H,66,80)(H,67,78)(H,68,79)(H,69,84)(H,70,87)(H,71,81)(H,72,85)(H,73,83)(H,74,82)(H,88,89,90)(H,91,92,93)(H,94,95,96)(H,97,98,99)(H,100,101,102);;;/q;3*+1/p-5
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: H2O : 100 mg/mL (Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Colistin methanesulfonate is less bactericidal than colistin at the same multiples of the MIC. Colistin and colistin methanesulfonate are both unequal mixtures of the salts of two components, colistins A and B (1), which may well have different in vitro activities.
Products are for research use only. Not for human use.
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