Cirazoline hydrochloride


Catalog No. Size PriceQuantity
M18652-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Cirazoline hydrochloride (LD 3098 hydrochloride) is a potent competitive full α1A-adrenergic receptor (α1A-AR) agonist (Ki=120 nM) and only a partial agonist at α1B-AR (Ki= 960 nM) and α1D-AR (Ki=660 nM).

Product information

CAS Number: 40600-13-3

Molecular Weight: 252.74

Formula: C13H17ClN2O

Chemical Name: 2-[(2-cyclopropylphenoxy)methyl]-4,5-dihydro-1H-imidazole hydrochloride

Smiles: Cl.C(OC1=CC=CC=C1C1CC1)C1NCCN=1

InChiKey: XFRXWLWUUDJHPB-UHFFFAOYSA-N

InChi: InChI=1S/C13H16N2O.ClH/c1-2-4-12(11(3-1)10-5-6-10)16-9-13-14-7-8-15-13;/h1-4,10H,5-9H2,(H,14,15);1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: H2O : 33.33 mg/mL (131.87 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Cirazoline hydrochloride (5-10 μM; 24 hours) does not alter GIC survival and counteracted only poorly prazosin‐induced GIC death.

In Vivo:

Cirazoline hydrochloride (drinking water; 40 μM; 9 month) exhibits significantly decreased immobility in the TST and enhances neurogenesis in the mouse.

Products are for research use only. Not for human use.

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