Iodophenpropit dihydrobromide


Catalog No. Size PriceQuantity
M18911-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Iodophenpropit dihydrobromide is a potent and selective histamine H3 receptor antagonist. The binding of [125I]Iodophenpropit is selective, saturable, readily reversible, and of high affinity (KD 0.32 nM).

Product information

CAS Number: 145196-87-8

Molecular Weight: 576.13

Formula: C15H21Br2IN4S

Chemical Name: (Z)-N'-[2-(4-iodophenyl)ethyl]{[3-(1H-imidazol-5-yl)propyl]sulfanyl}methanimidamide dihydrobromide

Smiles: Br.Br.N/C(=N/CCC1C=CC(I)=CC=1)/SCCCC1=CN=CN1

InChiKey: BOSOGNBLIWPCMS-UHFFFAOYSA-N

InChi: InChI=1S/C15H19IN4S.2BrH/c16-13-5-3-12(4-6-13)7-8-19-15(17)21-9-1-2-14-10-18-11-20-14;;/h3-6,10-11H,1-2,7-9H2,(H2,17,19)(H,18,20);2*1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Iodophenpropit is a very potent H3 receptor antagonist and shows only a moderate affinity for the H1 and H2 receptor. Iodophenpropit inhibit 5-hydroxytryptamine (5-HT) responses with an IC50 of 1.57±0.3 μM.

In Vivo:

Iodophenpropit (1 μg/kg; through intramuscular; b.i.d.; for 10 days) shows significant enhancement of total anti- sheep red blood cells (SRBC)- immunoglobulins (Igs) in rabbits.

Products are for research use only. Not for human use.

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