Description
A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A2A receptor and A1 receptor with Ki values of 4 and 264 nM, respectively.
Product information
CAS Number: 443103-97-7
Molecular Weight: 309.30
Formula: C16H12FN5O
Chemical Name: 1-[(2-fluorophenyl)methyl]-4-(furan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-amine
Smiles: NC1=NC2=C(C=NN2CC2=CC=CC=C2F)C(=N1)C1=CC=CO1
InChiKey: JEEJMSUHUZNTCD-UHFFFAOYSA-N
InChi: InChI=1S/C16H12FN5O/c17-12-5-2-1-4-10(12)9-22-15-11(8-19-22)14(20-16(18)21-15)13-6-3-7-23-13/h1-8H,9H2,(H2,18,20,21)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 25 mg/mL (80.83 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
A2A receptor antagonist 1 (CPI-444 analog) is a potent adenosine A2A receptor antagonist, selective over the A1 receptor and demonstrates its binding activity with Ki values of 4 and 264 nM, respectively.
Products are for research use only. Not for human use.
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