JAK-IN-10


Catalog No. Size PriceQuantity
M19048-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

JAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye disorders.

Product information

CAS Number: 916741-98-5

Molecular Weight: 427.45

Formula: C20H18FN5O3S

Chemical Name: 5-[(5-fluoro-4-{[4-(prop-2-yn-1-yloxy)phenyl]amino}pyrimidin-2-yl)amino]-2-methylbenzene-1-sulfonamide

Smiles: CC1=CC=C(C=C1S(N)(=O)=O)NC1N=C(NC2C=CC(=CC=2)OCC#C)C(F)=CN=1

InChiKey: YSWHPGYAPJLREH-UHFFFAOYSA-N

InChi: InChI=1S/C20H18FN5O3S/c1-3-10-29-16-8-6-14(7-9-16)24-19-17(21)12-23-20(26-19)25-15-5-4-13(2)18(11-15)30(22,27)28/h1,4-9,11-12H,10H2,2H3,(H2,22,27,28)(H2,23,24,25,26)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

JAK kinases are a family of cytoplasmic protein tyrosine kinases including JAK1, JAK2, JAK3 and TYK2. Each of the JAK kinases is selective for the receptors of certain cytokines, though multiple JAK kinases may be affected by particular cytokine or signaling pathways.

Products are for research use only. Not for human use.

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