S26131


Catalog No. Size PriceQuantity
M19066-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

S26131 (compound 5) is a potent and selective MT1 melatoninergic ligand, and the Ki values are 0.5 and 112 nM for MT1 and MT2, respectively. S26131 behaves as an MT1 and MT2 antagonist.

Product information

CAS Number: 296280-56-3

Molecular Weight: 498.61

Formula: C31H34N2O4

Chemical Name: N-{2-[7-(3-{[8-(2-acetamidoethyl)naphthalen-2-yl]oxy}propoxy)naphthalen-1-yl]ethyl}acetamide

Smiles: CC(=O)NCCC1=CC=CC2=CC=C(C=C12)OCCCOC1=CC2C(C=C1)=CC=CC=2CCNC(C)=O

InChiKey: NSXBZYDTTKLTOH-UHFFFAOYSA-N

InChi: InChI=1S/C31H34N2O4/c1-22(34)32-16-14-26-8-3-6-24-10-12-28(20-30(24)26)36-18-5-19-37-29-13-11-25-7-4-9-27(31(25)21-29)15-17-33-23(2)35/h3-4,6-13,20-21H,5,14-19H2,1-2H3,(H,32,34)(H,33,35)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 5 mg/mL (10.03 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

S26131 behaves as an antagonist on MT1 and MT2 receptors with KB values of 5.32 and 143 nM, respectively.

Products are for research use only. Not for human use.

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