Description
Sabutoclax is a potent and effective Bcl-2 Family (Bcl-2, Bcl-XL, Mcl-1, Bfl-1) inhibitor with IC50s of 0.32 μM, 0.31 μM, 0.20 μM, and 0.62 μM, respectively.
Product information
CAS Number: 1228108-65-3
Molecular Weight: 700.78
Formula: C42H40N2O8
Chemical Name: 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-N5,N5'-bis(2-phenylpropyl)-[2,2'-binaphthalene]-5,5'-dicarboxamide
Smiles: CC1C=C2C(C(=O)NCC(C)C3C=CC=CC=3)=C(O)C(O)=CC2=C(O)C=1C1=C(O)C2C=C(O)C(O)=C(C=2C=C1C)C(=O)NCC(C)C1C=CC=CC=1
InChiKey: RAYNZUHYMMLQQA-UHFFFAOYSA-N
InChi: InChI=1S/C42H40N2O8/c1-21-15-27-29(17-31(45)39(49)35(27)41(51)43-19-23(3)25-11-7-5-8-12-25)37(47)33(21)34-22(2)16-28-30(38(34)48)18-32(46)40(50)36(28)42(52)44-20-24(4)26-13-9-6-10-14-26/h5-18,23-24,45-50H,19-20H2,1-4H3,(H,43,51)(H,44,52)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 36.67 mg/mL (52.33 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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