Catalog No. Size PriceQuantity
M19131-C Contact sales@xcessbio.com for quotation $100Unavailable


PDE1-IN-2 is a PDE1 inhibitor extracted from patent WO2016/55618 A1, example 31. PDE1-IN-2 has IC50 values of 6 nM, 140 nM and 164 nM for PDE1C, PDE1B and PDE1A, respectvely. PDE1-IN-2 is developed for the research of neurodegenerative disorders and psychiatric disorders.

Product information

CAS Number: 1904611-63-7

Molecular Weight: 381.27

Formula: C16H21BrN4O2

Chemical Name: 6-bromo-7-(cyclopentylmethyl)-3-(oxan-4-yl)-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-8-one

Smiles: O=C1C2=NN=C(C3CCOCC3)N2C=C(Br)N1CC1CCCC1


InChi: InChI=1S/C16H21BrN4O2/c17-13-10-21-14(12-5-7-23-8-6-12)18-19-15(21)16(22)20(13)9-11-3-1-2-4-11/h10-12H,1-9H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 25 mg/mL (65.57 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PDE1 enzymes are expressed in the central nervous system (CNS), making this gene family an attractive source of new targets for the treatment of psychiatric and neurodegenerative disorders.

Products are for research use only. Not for human use.

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