IDO-IN-3

IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 290 nM.

Product information

CAS Number: 2070018-30-1

Molecular Weight: 359.15

Formula: C11H12BrFN6O2

Chemical Name: (E)-4-[(2-aminoethyl)amino]-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide

Smiles: NCCNC1=NON=C1/C(/NC1C=CC(F)=C(Br)C=1)=N\O

InChiKey: DAPNMIADTFAXEG-UHFFFAOYSA-N

InChi: InChI=1S/C11H12BrFN6O2/c12-7-5-6(1-2-8(7)13)16-11(17-20)9-10(15-4-3-14)19-21-18-9/h1-2,5,20H,3-4,14H2,(H,15,19)(H,16,17)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 27.5 mg/mL (76.57 mM; Need ultrasonic and warming).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

IDO-IN-3 (Compound 4c) is a potent (HeLa IC50=98 nM) inhibitor of IDO.

Products are for research use only. Not for human use.