Aurora B inhibitor 1

Catalog No. Size PriceQuantity
M19156-C Contact for quotation $100Unavailable


Aurora B inhibitor 1 is an Aurora B (Aurora-1) inhibitor extracted from patent WO2007059299A1, compound 1-3, has a Ki value of <0.010 uM.

Product information

CAS Number: 937276-52-3

Molecular Weight: 529.97

Formula: C25H26ClF2N7O2

Chemical Name: 2-{[(3S)-1-(5-chloro-2-fluorobenzoyl)pyrrolidin-3-yl]oxy}-6-(3-cyclopropyl-3-fluoroazetidin-1-yl)-N-(5-methyl-1H-pyrazol-3-yl)pyrimidin-4-amine

Smiles: CC1=CC(NC2=CC(=NC(=N2)O[C@@H]2CN(CC2)C(=O)C2C=C(Cl)C=CC=2F)N2CC(F)(C2)C2CC2)=NN1


InChi: InChI=1S/C25H26ClF2N7O2/c1-14-8-21(33-32-14)29-20-10-22(35-12-25(28,13-35)15-2-3-15)31-24(30-20)37-17-6-7-34(11-17)23(36)18-9-16(26)4-5-19(18)27/h4-5,8-10,15,17H,2-3,6-7,11-13H2,1H3,(H2,29,30,31,32,33)/t17-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Aurora B inhibitor 1 also inhibits JAK3 and JAK2 with Kis of <0.25 μM and <0.10 μM, respectively.

Products are for research use only. Not for human use.

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