CGRP antagonist 1


Catalog No. Size PriceQuantity
M19200-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

CGRP antagonist 1 is a highly potent CGRP receptor antagonist with a Ki and IC50 of 35 and 57 nM, respectively.

Product information

CAS Number: 1123757-49-2

Molecular Weight: 494.54

Formula: C29H26N4O4

Chemical Name: N-[(2S)-2'-oxo-1,1',2',3-tetrahydrospiro[indene-2,3'-pyrrolo[2,3-b]pyridin]-6-yl]-2-{2-oxo-1,2-dihydrospiro[indole-3,4'-oxan]-1-yl}acetamide

Smiles: O=C(CN1C2C=CC=CC=2C2(CCOCC2)C1=O)NC1=CC2C[C@@]3(CC=2C=C1)C1=CC=CN=C1NC3=O

InChiKey: HGRHCVKYWPUJJT-LJAQVGFWSA-N

InChi: InChI=1S/C29H26N4O4/c34-24(17-33-23-6-2-1-4-21(23)28(27(33)36)9-12-37-13-10-28)31-20-8-7-18-15-29(16-19(18)14-20)22-5-3-11-30-25(22)32-26(29)35/h1-8,11,14H,9-10,12-13,15-17H2,(H,31,34)(H,30,32,35)/t29-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

CGRP antagonist 1 is compound 20.

Products are for research use only. Not for human use.

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